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Pragmatic trials are those that are designed to inform the real-world practice of clinical. They are typically described by their focus on practical aspects of designing a study which include the recruitment process and consent, adhering and the use of routinely available equipment.

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Another example of a trial that is pragmatic is the Home Blood Pressure Management (HBPM) study, which used different investigators and participants from various geographical areas. This type of heterogeneity, which is essential for a pragmatic trial to be reliable and lessen the chance of bias is also essential. However excessive heterogeneity could result in problems with the design of the trial.

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Mobile compatibility

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Legality

Pragmatic Play is known for its top-quality games and for offering an exceptional user experience. Its software can be used on mobile devices as well as in various languages. Despite its relative youth, it has already established itself as a leading gaming platform for casinos. Wolves is one of the most recent releases that is a 5-reel slot machine that has a high RTP and impressive graphics. The other notable titles include Wolf Gold and Chilli Heat.

The goal of pragmatic trials is to mimic real-life situations and achieve the highest level of validity externally. They are usually ordered by policymakers and practitioners to inform their decisions. They can also be used to assess the cause-effect relationship of an intervention and its effects. However, they should not be used as a substitute for explanation trials.

The concept of pragmatism is controversial, and there are questions about whether pragmatic trials should be used to replace explanatory trials or complement them. Schwartz and Lellouch1 suggested a distinction between explanatory trials, which validate the validity of a clinical or physiological hypothesis, and pragmatic trials that inform the policy and practice of. They also suggested a framework known as PRECIS for pragmatic trials.2 This tool tried to define the traits of a pragmatic study that includes the recruitment, design, and delivery of the intervention, and follow-up.

The number of pragmatic trials is growing. A recent Medline search using the keywords pragmatic and naturalistic, restricted to randomized controlled trials (RCTs), yielded 34 articles, which are shown in red in Figure 2. This is an indication that the health sciences community is becoming more acquaint to the issue of pragmatic thinking. It is important to note, however, that the majority of these studies were conducted in primary-care settings.